Metabolic Research Institute
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The MRI Endo-Pedia

Welcome to the MRI "Endo-pedia" . . . an encyclopedia of information related to specific Metabolic Disorders.

You can access a particular site by clicking on the icon adjacent to the description of the linked internet website or the "For More Information" button.

I.  CUSHING'S SYNDROME

Cushing's syndrome is a hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. Sometimes called "hypercortisolism," it is relatively rare and most commonly affects adults aged 20 to 50. An estimated 10 to 15 of every million people are affected each year.

Who gets it?  What are its symptoms?  What causes Cushing's syndrome?  How is it diagnosed?  How can it be treated?  Can Cushing's syndrome be cured?  What about the future?


II.  PARATHYROID   THYROID    ADRENAL

This web site reviews Thyroid, Parathyroid, Adrenal, and Pancreas disorders, including Diabetes and Osteoporosis. This information is intended for the education of patients and their families. Pages at least twice weekly and now include a very large amount of information on endocrine disease, conditions, hormone problems, and treatment options including all types of thyroid, parathyroid, and adrenal surgery. 


How to give an emergency injection of Efcortesol®
In an emergency extra steroid medication may be needed via an emergency injection of hydrocortisone. This pictorial guide provides step by step guidance on how to administer the injection.


III.  THE T3/T4 CONTROVERSY

Does the treatment of hypothyroidism with T3 (triiodothyronine) in addition to T4 (thyroxine) have a scientific as well as a clinical basis?
Is it possible that, f
or many hypothyroid patients, supplementing with T4 alone does not constitute adequate treatment?

Read what some of the leading medical experts are saying . . .
 

 

IV.  HYPERPARATHYROIDISM

 

The primary disease of parathyroid glands is overactivity...too much parathyroid hormone is produced. This is called hyperparathyroidism. Under this condition, one or more of the parathyroid glands behaves inappropriately by making excess hormone regardless of the level of calcium. In other words, the parathyroid glands continue to make large amounts of parathyroid hormone even when the calcium level is normal and they should not be making hormone at all.


 

V.  POLYCYSTIC OVARIES
 

In women, the ovaries secrete the female hormones estrogen and progesterone and also the so-called male hormones. The male hormones include testosterone, androstenedione and dehydroepiandro-sterone (DHEA) and are called androgens. In polycystic ovary syndrome (PCOS), a woman's body produces an excess of male hormones, which may lead to acne and excess hair growth. The ovaries release eggs (ovulation) less frequently than normal (oligo-ovulation), or they don't release eggs at all (anovulation). In the absence of ovulation, the menstrual cycle is irregular or absent.

 


VI.  MISCELLANEOUS SYNDROMES

At this site, you will find information and patient fact sheets with regard to endocrinology and its relationship to many other medical conditions.