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A United Kingdom study involving over 10,000 people with diabetes showed that over time, the pancreas of diabetics produced less and less insulin. Patients initially treated with diet alone to control their diabetes eventually needed one medication, then two medications, and eventually, many patients involved in the trial required insulin.

The reason why the pancreas deteriorated over time is unknown. Some researchers concur that, if the right drug can be found, we can preserve remaining pancreatic function. While this issue is still under investigation, there is significant evidence that some of the newer diabetic medications have properties that can preserve pancreatic function by halting the progressive loss of insulin-producing cells.

“This is one of the most exciting areas of research in which we are currently working,” states William Kaye, M.D., F.A.C.P., Co-Director with Barry Horowitz, M.D., F.A.C.P., of the Metabolic Research Institute. MRI is currently studying several promising medications. “The implications are enormous,” adds Dr. Horowitz. “Imagine blood sugars being controlled with just one medication and no worry about the pancreas failing in the future. Imagine excellent control without insulin. Someday this will be more than just a dream.”

In the meantime, the Metabolic Research Institute is conducting several research studies on diabetes. Whether you are currently on no medication for your diabetes, or on one or more agents, there may be a clinical trial that will fit your needs. We are presently conducting a study with a medication that has been also shown to help with weight loss. The benefits of participating include study medication, examinations, and laboratory tests . . . all at no expense to you. In addition, some trials reimburse participants for time and travel.




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